Life, the Universe and Everything

Life, the universe and everything is a line from a book titled, The Hitchhikers Guide to the Galaxy.  The title was first used in reference to a 1978 BBC Radio Comedy that became a TV series and made it's way into computer gaming, more Tv series, comic books, a novel and the movies.

The novel, by the author, Douglas Adams is a story that begins with a brief narrative of human history from the beginning of time; a sort of history of "Evolution," about how mankind previously to what he is today being some form of arboreal ape that "came down out of the trees" (and has been regretting it ever since.)  Hitchhikers Guide is in it's totality, a cosmic, albeit comic tale, of a man who is rescued via spacecraft from an exploding earth and travels the galaxies of space via the wisdom of little book and traveling companion... an alien being who becomes his friend, just at the nick of time when Earth is finally, at the very end of what is now known to man, destroyed. 

Having been saved from destruction, this hitchiker, Authur Dent, and his new found alien friend, with the help of the guide book, a highly technologically advanced device by which everything aboutt he univerwe can be known, travel, enounter beings of strange origin and have adventures where they trun into things like couches.  The guide book, it should be noted, is reminiscent of a bible, but it's not a Bible, just a Hitchhikers Guide to the Universe, which is said to be, (pun intended no doubt by Douglas Adams himself,) a “wholly" (or it is "holy.") "remarkable book.”

From the very intro this evolutionary based, atheistic sci-fi fantasy makes reference to religion and the references to Christianity are not subtle.  In preface, the reader is informed that the story about to be read took place just as a girl, sitting in a cafe, was thinking about how some guy got hung on a tree about 2000 years ago for telling everyone that the world would be a better place if everyone would just be nice to each other, an obvious, (or maybe not so obvious?) reference to Jesus Christ.

The girl, as we learn, just then got an idea about how the time was right to make the world a better place... and this was so that no one would have to get hung on a tree.  However, (sadly) just before she was able to tell anyone her great idea.... (you guessed it...)  the earth was destroyed (except for Authur Dent) and the idea she had, as well as herself, was now lost forever. The reader is then informed that the book, Hitchhikers Guide, is not her story, but  rather: “it is the story of the terrible, stupid, catastrophe,” in which she lost her meaningless life and presumably great thought about how to make the world a better place.... and that guy who hung on the tree 2000 years ago.. obviously for nothing, because Earth is no more, and Aurthur is busy making a dent in the galaxy.

Douglas Adams himself never got to see the modern movie. Adams, a professed atheist who no doubt knew a lot about the guy who hung on a tree 2000 years ago, died at the age of 49 of a heart attack.
Throughout his life, Adams emphatically said he was convinced there was no God, (having never seen any evidence to convince him otherwise,) and his work certainly reflects his beliefs. He was however quite amused that "otherwise rational... intelligent people..” who take belief in God seriously, and so, he says, his work is a reflection of that.